Find a clinical trial

A clinical trial is a research study that people can join. Some test a new treatment. Some test a new way to use a treatment we already have. Joining one is always your choice.

Trials near you

Enter your ZIP code to see open trials with a site within 50 miles. We use your ZIP only to run that search. We do not store it.

Browse trials

Showing 294 trials. Trials we know are closed are left out. This list is the brain tumor trials we track, not every trial on ClinicalTrials.gov. The search above looks at all of them.

• A long-term study of people with neurofibromatosis type 2 and how their tumors and symptoms change

  Recruiting Maryland

  This study follows people with neurofibromatosis type 2 over time to learn why tumors and nerve problems get worse.

• Testing a new antibody drug called GNC-039 in people with glioma or other solid tumors

  Recruiting Phase 1 Beijing Municipality, Chongqing Municipality, Guangdong, Shanxi, and more

  This trial is testing how safe a new drug called GNC-039 is in people whose tumor has come back or spread.

• A study of the drug zotiraciclib for gliomas with IDH1 or IDH2 gene changes

  Recruiting Phase 1/Phase 2 Maryland

  This study tests a capsule called zotiraciclib in people whose brain tumor came back.

• Testing a scan tracer called FET to find brain tumors

  Recruiting California

  This study is testing a substance called FET to help spot brain tumors on scans.

• Testing silevertinib added to temozolomide for newly diagnosed glioblastoma

  Recruiting Phase 2 Alabama, Arkansas, California, Connecticut, and more

  This trial is testing whether adding a drug called silevertinib to temozolomide works better than temozolomide alone.

• A study of mood, worry, and suicidal thoughts in people with glioblastoma

  Recruiting

  This study asks people with glioblastoma about depression, anxiety, and thoughts of suicide.

• Testing engineered immune cells for H3K27M diffuse midline glioma and DIPG

  Not yet recruiting Phase 1/Phase 2 Guangdong

  This study tests immune cells built to target a tumor change called H3K27M.

• Collecting spinal fluid and blood samples from people with breast cancer that has spread outside the brain

  Not yet recruiting Maryland

  This study collects fluid and tissue samples to look for signs that breast cancer may spread to the brain.

• A test of safusidenib for IDH1-mutant glioma that grew during vorasidenib treatment

  Not yet recruiting Phase 2 California, Connecticut, Indiana, New Jersey, and more

  This trial is testing a drug called safusidenib in people whose glioma grew while they were taking vorasidenib.

• Hyperbaric oxygen added to drug treatment for newly found glioblastoma

  Not yet recruiting Phase 2

  This study tests if hyperbaric oxygen helps drug treatment work better for glioblastoma.

• A drug called Sac-TMT with brain radiation for lung cancer that spread to the brain

  Not yet recruiting Phase 2

  This trial asks if a new drug plus brain radiation can slow brain tumors.

• A study of people in Brazil with IDH-mutant diffuse glioma

  Not yet recruiting Estado de Bahia, Federal District, Minas Gerais, Rio de Janeiro, and more

  This study looks back at the health records of people in Brazil who have a brain tumor called IDH-mutant diffuse glioma.

• Proton radiation aimed away from the brain for cancer that has spread to the fluid around the brain and spine

  Not yet recruiting Phase 2 Florida

  This study tests a form of proton radiation for adults whose solid tumor cancer has spread to the lining of the brain and spine.

• Nerve signal checks during brain tumor surgery in adults

  Not yet recruiting Not applicable Fyn

  This study tests if signal checks during surgery protect movement, speech, and sight.

• Testing FPS-ZM1 for brain swelling after glioblastoma surgery

  Not yet recruiting Phase 1 California

  This study is testing a drug to see if it can help control brain swelling after glioblastoma surgery.

• Comparing two seizure drugs in people with glioma

  Recruiting Phase 4

  This trial compares two seizure medicines in people with a brain tumor called glioma.

• A Vaccine Made From a Person's Own Immune Cells for Brain Tumors

  Not yet recruiting Phase 1 Guangdong

  This study tests a vaccine built from a person's own immune cells.

• Testing a radiation bead treatment for glioblastoma that has come back

  Recruiting Phase 1 Alabama, California, Florida, Illinois, and more

  This study is testing whether a device that places tiny radiation beads into a brain tumor is safe for people whose glioblastoma has returned.

• Testing selinexor added to usual chemotherapy for glioblastoma that has come back

  Recruiting Phase 1/Phase 2 Arizona, California, Colorado, Florida, and more

  This study is testing whether adding a drug called selinexor to the usual chemotherapy helps people whose brain tumor has returned.

• Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

  Recruiting Phase 1 Florida

Trial information comes from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. We copy it as it is published there and do not change it. Always check the trial's own page for the latest.