Testing metformin for PFA ependymoma that has come back or is growing
Official title: Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on .
The short version
This trial is testing a drug called metformin in children and young adults whose PFA ependymoma has come back or is growing.
Read our full plain-language summary
What the trial team says
This is a multi-site study of the pharmacodynamic effects and efficacy of metformin in children and young adults with recurrent or progressive Posterior Fossa Group A (PFA) ependymoma.
Key facts
- Registry number
- NCT07226453
- Stage of testing
- Phase 2
- Conditions studied
- Posterior Fossa Ependymal Tumor
Where it is running
This trial lists 10 sites.
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Alabama
- University of Alabama at Birmingham (Birmingham)
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California
- University of California, San Francisco (San Francisco)
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District of Columbia
- Children's National Medical Center (Washington D.C.)
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Maryland
- Johns Hopkins University (Baltimore)
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Michigan
- University of Michigan (Ann Arbor)
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Missouri
- Washington University (St Louis)
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New Jersey
- Hackensack Meridian Health (Hackensack)
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North Carolina
- Duke University (Durham)
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Tennessee
- St. Jude Children's Research Hospital (Memphis)
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Utah
- University of Utah (Salt Lake City)
How to use this
Talk to your care team first. They know your history and can tell you whether this trial is worth your time.
Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.
This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.