Find a clinical trial

A clinical trial is a research study that people can join. Some test a new treatment. Some test a new way to use a treatment we already have. Joining one is always your choice.

Trials near you

Enter your ZIP code to see open trials with a site within 50 miles. We use your ZIP only to run that search. We do not store it.

Browse trials

Showing 294 trials. Trials we know are closed are left out. This list is the brain tumor trials we track, not every trial on ClinicalTrials.gov. The search above looks at all of them.

• Testing the drug AMXT 1501 with eflornithine (DFMO) for neuroblastoma, brain and spinal cord tumors, and sarcomas

  Recruiting Phase 1/Phase 2 Alabama, Arkansas, Connecticut, Florida, and more

  This study is testing an experimental pill, AMXT 1501, taken together with a pill called eflornithine (DFMO).

• Testing the drug M3554 in people with advanced soft tissue sarcoma or glioblastoma

  Recruiting Phase 1 Massachusetts, New York, Surrey, Texas

  This study is testing a drug called M3554 to find the right dose and to watch for side effects.

• A study of the drug ACT001 for DIPG and H3K27-altered high grade glioma

  Recruiting Phase 2 Baden-Wurttemberg, Colorado, District of Columbia, Florida, and more

  This study is testing a drug called ACT001 in people with certain brain tumors.

• Testing a new drug called PHST001 in adults with advanced solid tumors

  Recruiting Phase 1 California, Colorado, Connecticut, Illinois, and more

  This study is testing whether a new drug, PHST001, is safe for adults whose cancer has come back or kept growing.

• A remote exercise program for young brain tumor survivors who feel very tired

  Recruiting Not applicable Texas

  This study is testing whether a guided exercise program can help young brain tumor survivors who deal with deep tiredness from cancer.

• Testing CAR T cells put into the brain for high-grade glioma that came back or is getting worse

  Recruiting Phase 1 California

  This trial is testing a treatment made from a person's own immune cells, placed right into the brain.

• A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving Pembrolizumab

  Recruiting Phase 1 California

• Studying blood and urine during radiation for glioblastoma

  Recruiting Maryland

  This study looks at what happens in the blood and urine of people getting radiation for a brain tumor called glioblastoma.

• A study of balance after Gamma Knife treatment for a vestibular schwannoma

  Recruiting Not applicable

  This study follows how balance changes in people treated with Gamma Knife radiation for a benign tumor near the hearing and balance nerve.

• Testing a treatment plan built for each person's tumor in children and young adults whose medulloblastoma or ependymoma has come back

  Recruiting Not applicable California, District of Columbia, Minnesota, Missouri, and more

  This study tests whether a care team can build a treatment plan that fits one person's own tumor.

• Testing a GD2 CAR T cell therapy in children and young adults with diffuse midline glioma

  Recruiting Phase 1

  This study is testing a CAR T cell therapy aimed at GD2 in young people with a brain tumor called diffuse midline glioma.

• A study testing doses of BI 764532 in people with a DLL3 positive brain tumor

  Recruiting Phase 1 California, Tennessee

  This study is testing how much of a drug called BI 764532 people with a brain tumor can handle.

• Mirdametinib with vinblastine chemotherapy for newly diagnosed PLGG

  Recruiting Phase 1/Phase 2 Alberta, British Columbia, Manitoba, Ontario, and more

  This study is testing a drug taken by mouth, mirdametinib, given together with vinblastine chemotherapy in people with newly diagnosed PLGG.

• Testing a targeted radiation drug with lomustine for glioblastoma that has come back

  Recruiting Phase 3 Queensland, Victoria, Western Australia

  This trial is testing whether adding a targeted radiation drug to lomustine helps adults whose glioblastoma has come back.

• Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

  Recruiting Phase 4 California, New York

• Testing levetiracetam added to standard treatment for hypoxic IDH-wildtype glioblastoma

  Not yet recruiting Phase 2 Tianjin Municipality

  This study asks if adding a drug called levetiracetam to the usual glioblastoma treatment helps people do better.

• Adding lenalidomide and nivolumab to the usual drugs for primary CNS lymphoma

  Recruiting Phase 1 California, Florida, Iowa, Louisiana, and more

  This study is testing whether two added drugs can help treat lymphoma in the brain and spinal cord.

• Placing a small fluid port during brain tumor surgery to collect samples for research

  Recruiting Not applicable Minnesota

  This study is testing whether a small device called an Ommaya reservoir can be placed safely during brain tumor surgery so doctors can collect fluid from around the brain over time.

• Testing two drugs after focused radiation for lymphoma in the brain and spinal cord

  Recruiting Phase 1 Pennsylvania, Rhode Island, Utah

  This study is testing whether two drugs given after focused radiation are safe and helpful for people with lymphoma in the brain or spinal cord.

• Testing a phone app to deliver glioma treatment at home

  Recruiting Not applicable Florida, Minnesota

  This study is testing a mobile app that lets people with glioma get therapy at home and stay in touch with their care team.

Trial information comes from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. We copy it as it is published there and do not change it. Always check the trial's own page for the latest.