Comparing two radiation plans for large tumors that spread to the brain
Official title: Brain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT)
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on .
The short version
This study compares two common ways to give focused radiation to large brain tumors that came from cancer elsewhere in the body.
Read our full plain-language summary
What the trial team says
This is a randomized, phase II trial comparing staged stereotactic radiosurgery (SSRS) versus fractionated stereotactic radiotherapy (FSRT) in patients with large brain metastases (≥2 cm and ≤5 cm). The study aims to evaluate efficacy, safety, and tumor response between these two standard-of-care radiation approaches.
Key facts
- Registry number
- NCT07227610
- Stage of testing
- Phase 2
- Conditions studied
- Brain Metastases, Cancer (With CNS Involvement)
Where it is running
This trial lists 1 site.
-
South Carolina
- Medical University of South Carolina Hollings Cancer Center (Charleston)
How to use this
Talk to your care team first. They know your history and can tell you whether this trial is worth your time.
Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.
This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.