Vitamin B6 for mood side effects of levetiracetam in people with brain tumors
Original title: B6 Administration for Levetiracetam-Associated Neurobehavioral Changes and Epilepsy
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This study does not list a phase, and it is still being tested in people.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study is testing whether a daily vitamin B6 supplement helps with mood side effects from a seizure medicine.
Who this trial is for. This study is for people with brain tumors who are already taking levetiracetam to prevent seizures. They take vitamin B6 as a daily supplement for 8 to 12 weeks, and both the patient and an optional caregiver fill out questionnaires about the patient's mood.
Where it stands. This trial has not reported results. It is measuring mood, rated by the patient and by a caregiver. The answer is not in yet.
What this means, and what it doesn't
What it could mean: Mood changes from levetiracetam are hard to live with. This study is looking at one simple idea that might help. If you have a brain tumor and take levetiracetam, you could ask your care team whether a study like this is worth looking into for you.
What it doesn't mean: This does not mean vitamin B6 is a proven fix for these mood changes. A trial is a test. It is not treatment your doctor can give you as standard care. Being in a study is not a promise that you will feel better. It is not a cure, and it is not treatment for the tumor itself. Do not start a supplement on your own. Talk to your care team first.
Source: ClinicalTrials.gov, July 29, 2026 · Read the original
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