Find a clinical trial

A clinical trial is a research study that people can join. Some test a new treatment. Some test a new way to use a treatment we already have. Joining one is always your choice.

Trials near you

Enter your ZIP code to see open trials with a site within 50 miles. We use your ZIP only to run that search. We do not store it.

Browse trials

Showing 294 trials. Trials we know are closed are left out. This list is the brain tumor trials we track, not every trial on ClinicalTrials.gov. The search above looks at all of them.

• Testing the drug datopotamab deruxtecan for breast cancer that has spread to the brain

  Recruiting Phase 2 Florida, Massachusetts, North Carolina

  This study is testing a drug called datopotamab deruxtecan in people whose breast cancer has spread to the brain.

• Sitagliptin, a diabetes drug, tested in people with growing grade 4 glioma

  Recruiting Phase 2 Ohio

  This study tests whether a drug used for diabetes can help the immune system fight a grade 4 brain tumor.

• Two ways of giving whole brain radiation for cancer that has spread to the brain

  Recruiting Phase 2 Ohio

  This study compares two forms of whole brain radiation to see which one better protects a person's thinking and memory.

• A shorter course of radiation with three drugs for newly diagnosed lymphoma that starts in the brain or spinal cord

  Recruiting Phase 2 Fujian

  This study is testing whether a short radiation course plus three drugs can help people just diagnosed with a lymphoma that starts in the brain or spinal cord.

• Testing the drug paxalisib in people whose central nervous system lymphoma has come back

  Recruiting Phase 2 Massachusetts

  This study is testing a drug called paxalisib in people with primary central nervous system lymphoma that came back or did not respond to earlier treatment.

• Testing an Immune Cell Treatment Made From a Person's Own Brain Tumor

  Recruiting Early phase 1 Jiangsu

  This trial is testing a treatment that uses immune cells taken from a person's own glioma.

• Testing a Keto Diet Alongside Usual Treatment for Newly Diagnosed Glioblastoma

  Recruiting Phase 2 California, North Carolina, Wisconsin

  This study is testing whether a keto diet helps people with a new glioblastoma live longer than standard diet advice does.

• Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU

  Recruiting Arizona, California, Connecticut, Illinois, and more

• Ommaya Reservoir Placement at the Time of Biopsy for Longitudinal Biomarker Collection in Patients With Brain Tumors

  Recruiting Not applicable Minnesota

• Testing a daily pill to keep CNS lymphoma from coming back

  Recruiting Phase 2

  This trial is testing whether a daily pill can help keep primary CNS lymphoma from returning after treatment clears it.

• Adding vorasidenib to temozolomide after radiation for grade 3 astrocytoma

  Recruiting Phase 3 California, Connecticut, Delaware, Illinois, and more

  This trial is testing whether adding a drug called vorasidenib to usual chemotherapy helps people with newly diagnosed grade 3 astrocytoma.

• NuvOx Expanded Access

  Available

• Testing bortezomib with temozolomide for grade-4 glioma that has come back

  Recruiting Phase 1/Phase 2

  This study tests two drugs given together in people whose grade-4 brain tumor has returned.

• Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors

  Recruiting Phase 1 California, Pennsylvania, Texas

• Brain mapping before radiation planning after surgery for a brain metastasis near the movement area

  Recruiting Not applicable

  This study is testing whether a brain map can help doctors aim radiation away from the part of the brain that controls movement.

• Testing a CAR T immune cell therapy, BCB-276, for children and young adults with DIPG

  Recruiting Phase 2 California, Georgia, Illinois, Ohio, and more

  This study is testing an immune cell therapy for DIPG, given after radiation.

• A drug combination tested for HR positive, HER2 negative breast cancer that has spread to the brain

  Not yet recruiting Phase 2 Guangdong, Hebei, Henan, Jiangsu, and more

  This study is testing whether adding another drug to hormone therapy can help control breast cancer that has spread to the brain.

• Testing a focused radiation treatment for cancer that has spread to the brain

  Recruiting Not applicable New York

  This study is testing how safe a focused form of radiation is for people with brain tumors that started as cancer somewhere else.

• Testing GD2 CAR T cells for brain tumors that carry the GD2 protein

  Recruiting Phase 1 Texas

  This study is testing immune cells that are changed in a lab to find and attack brain tumor cells that carry a protein called GD2.

• Post-Market Clinical Follow-Up Study on the Safety and Performance of Ennovate® Cervical

  Recruiting Free and Hanseatic City of Hamburg, Lower Saxony, Saxony, Saxony-Anhalt

Trial information comes from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. We copy it as it is published there and do not change it. Always check the trial's own page for the latest.