Find a clinical trial
A clinical trial is a research study that people can join. Some test a new treatment. Some test a new way to use a treatment we already have. Joining one is always your choice.
How to think about a clinical trial covers what taking part involves, when to ask, and what the phases mean.
Talk to your care team before you contact a trial. They know your history and can tell you whether a trial is worth your time. Nothing on this page is medical advice, and we are not part of any trial.
Trials near you
Enter your ZIP code to see open trials with a site within 50 miles. We use your ZIP only to run that search. We do not store it.
This box works for US ZIP codes only. Outside the US, use the country filter below to see trials in your country. It will not tell you how far away they are.
Trials by countries
Showing 478 trials. Trials we know are closed are left out. This list is the brain tumor trials we track, not every trial on ClinicalTrials.gov. The search above looks at all of them.
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Testing focused radiation after drug treatment for cancer that spread to the brain
This trial tests adding focused radiation to brain tumors after drug treatment.
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Testing the drug tarlatamab with radiation in tumors that make DLL3
This trial is checking whether a drug called tarlatamab is safe to give along with radiation.
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A Study Testing the Drug Zanzalintinib for Meningioma That Has Come Back or Is Growing
This trial is testing a drug called zanzalintinib in people whose meningioma has come back or keeps growing.
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Testing a dye that may show the edges of a brain tumor during surgery
Doctors are testing a dye that may help them see where a brain tumor ends.
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A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)
From the trial team: This is an open-label, multicenter Phase 2 study evaluating BMS-986504 in participants with advanced and/or metastatic solid tumors that have MTAP deletion.
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Testing a ketogenic diet or ketone drink in people with glioma that came back
This study looks at whether a high fat diet or a ketone supplement is safe and doable before brain surgery.
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Testing high-dose methotrexate for breast cancer that has spread to the brain lining
This study tests high-dose methotrexate for breast cancer that spread to the brain lining.
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Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
From the trial team: This study will assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary efficacy of AZD9574 individually and in combination with anti-cancer agents in participants with advanced cancer that has recurred/progressed.
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Testing an ultrasound device with chemotherapy for glioblastoma that has come back
This trial tests whether opening the brain's natural shield with sound waves helps a chemo drug reach a glioblastoma that has come back.
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A study testing doses of BI 764532 in people with a DLL3 positive brain tumor
This study is testing how much of a drug called BI 764532 people with a brain tumor can handle.
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Comparing gene changes in colorectal cancer that has spread to the brain
This study compares gene changes in the first colon tumor and the brain tumor.
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Recording brain cell activity during surgery for a glioma
This study listens to how brain cells fire next to a brain tumor during surgery.
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Testing a new drug called PHST001 in adults with advanced solid tumors
This study is testing whether a new drug, PHST001, is safe for adults whose cancer has come back or kept growing.
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A radiation implant placed during brain surgery for glioblastoma, compared with usual care
This study compares surgery alone with surgery plus a radiation implant for people with glioblastoma.
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Comparing tumor markers in stomach and esophagus cancers that spread to the brain
This study checks if a brain tumor carries the same markers as the cancer it came from.
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Real Time Craniotomy Planning Using Mixed Reality
From the trial team: This study is a prospective observational study designed to evaluate the effectiveness of Brainlab's Mixed Reality Viewer in enhancing the accuracy and efficiency of preoperative craniotomy planning.
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Testing mirdametinib, alone or with radiation, for NF1-related high-grade glioma
This study tests a drug called mirdametinib in people with high-grade glioma tied to NF1 gene changes.
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Dexbrompheniramine with daily temozolomide for high grade glioma that came back
This trial tests adding a drug called dexbrompheniramine to daily temozolomide.
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A long-term study of people with neurofibromatosis type 2 and how their tumors and symptoms change
This study follows people with neurofibromatosis type 2 over time to learn why tumors and nerve problems get worse.
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Brain surgery for tumors that cause seizures
This study tests brain surgery for people whose brain tumor causes seizures.
Trial information comes from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. We copy it as it is published there and do not change it. Always check the trial's own page for the latest.