Testing SX-682 with proton radiation for cancer that has spread to the lining of the brain and spine
Official title: A Study of SX-682 in Combination With Proton Craniospinal Irradiation (pCSI) in People With Leptomeningeal Disease
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on .
The short version
This study is testing whether a drug called SX-682, given with a type of radiation, is safe for people whose melanoma or lung cancer has spread to the lining of the brain and spine.
Read our full plain-language summary
What the trial team says
The researchers are doing this study to find out whether SX-682 in combination with proton craniospinal irradiation (pCSI) is a safe treatment approach for people with melanoma or non-small cell lung cancer (NSCLC) with leptomeningeal disease (LMD). The researchers will also look at whether the treatment combination is effective against participants' cancer.
Key facts
- Registry number
- NCT07814352
- Stage of testing
- Phase 1
- Conditions studied
- Leptomeningeal Disease (LMD)
Where it is running
This trial lists 7 sites.
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New Jersey
- Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities) (Basking Ridge)
- Memorial Sloan Kettering Monmouth (Limited Protocol Activities) (Middletown)
- Memorial Sloan Kettering Bergen (Limited Protocol Activities) (Montvale)
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New York
- Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Limited protocol activities) (Commack)
- Memorial Sloan Kettering Commack (Limited Protocol Activities) (Commack)
- Memorial Sloan Kettering Westchester (Limited Protocol Activities) (Harrison)
- Memorial Sloan Kettering Nassau (Limited Protocol Activities) (Uniondale)
How to use this
Talk to your care team first. They know your history and can tell you whether this trial is worth your time.
Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.
This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.