Special brain scans to help guide tube placement in glioma surgery

Official title: Multiparametric Metabolic and Hypoxic PET/MRI Imaging Substudy in Gliomas

Status: Not yet recruiting. It has not opened yet. Ask your care team to watch for it if it looks like a fit.

The trial team last updated this record on .

The short version

This study tests whether new scans can help doctors place treatment tubes in the brain.

Read our full plain-language summary

What the trial team says

This substudy will investigate a new imaging approach using positron emission tomography (PET) and two investigational drugs (\[18F\]FET and \[18F\]FMISO) to see if the imaging results will help with the placement of catheters for therapy delivery in 20 adult patients with malignant gliomas (MGs) who are participating in the UAB IRB approved main study, A Phase I/II Study of Pembrolizumab and M032 (NSC 733972), a Genetically Engineered HSV-1 Expressing IL-12, in Patients with Recurrent/Progressive and Newly Diagnosed Glioblastoma Multiforme, grade 3 or grade 4 astrocytoma, or Gliosarcoma (IRB 300007756 PI Markert). The PET and MR imaging results will be available to guide catheter placement within IRB 300007756 study-specific guidelines during Neurosurgery.

From the trial's own listing on ClinicalTrials.gov.

Key facts

Registry number
NCT07778979
Stage of testing
Early phase 1
Conditions studied
Glioma

Where it is running

This trial lists 1 site.

How to use this

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See the full listing on ClinicalTrials.gov

This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.