Testing disulfiram before brain surgery in people with high grade glioma
Official title: Study of Disulfiram to Reduce Myeloid Immunosuppression and Steroid Dependence in Resectable High Grade Glioma
Status: Not yet recruiting. It has not opened yet. Ask your care team to watch for it if it looks like a fit.
The trial team last updated this record on .
The short version
This study is looking at whether an older drug, given before surgery, can make a brain tumor easier for the immune system to fight and cut down on brain swelling.
Read our full plain-language summary
What the trial team says
This research study is for participants with glioblastoma. It can cause a tumor immunosuppression which helps myeloid cells that can stop T-cell function. Disulfiram is a drug that has been used in treating other disorders, but this study will examine if disulfiram can help make the tumor environment less immunosuppressive and reduce brain swelling when taken before surgery.
Key facts
- Registry number
- NCT07719127
- Stage of testing
- Phase 1
- Conditions studied
- Brain (Nervous System) Cancers
Where it is running
This trial lists 1 site.
-
Ohio
- University Hospitals Cleveland Medical Center (Cleveland)
How to use this
Talk to your care team first. They know your history and can tell you whether this trial is worth your time.
Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.
This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.