Testing Whether Gene Testing of Tumor Tissue or Blood Helps Guide Treatment Choices
Official title: The Added Value of Tissue or Liquid Biopsy NGS Profiling in Advanced Solid Tumor Treatment Decisions.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on .
The short version
This trial looks at whether detailed gene testing of a tumor sample or a blood sample helps doctors pick the next treatment.
Read our full plain-language summary
What the trial team says
A total of 550 patients with metastatic solid tumors or primary CNS malignancy will be recruited on a first come first serve basis at one of the 14 participating centers : UZL, UZG, Imelda, ZAZ, AZ Klina, CHU Liège, GHdC, CHU UCL Namur, IJB, UZB, CUSL, UZA, VITAZ and Jessa Zh.. \> 500 patients with tissue available will undergo CGP centrally at UZ Leuven (Roche AVENIO Tumor Tissue CGP kits, Novaseq platform). \> 50 patients without tissue available will undergo liquid biopsy testing at Foundation Medicine (FoundationOne Liquid CDx). The sequencing data generated by UZ Leuven laboratory will then be further analysed (secondary and tertiary analysis) by one of the eight laboratories participating in the study: UZL, UZG, IJB, CUSL, IPG, UZA, Jessa zh. and CHU Liège.
Key facts
- Registry number
- NCT07713550
- Conditions studied
- Advanced Solid Tumor Cancer, Primary CNS Tumors
Where it is running
This trial lists 14 sites.
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Belgium
- Institute Jules Bordet (Anderlecht)
- ZAS (Antwerp)
- Imelda (Bonheiden)
- AZ Klina (Brasschaat)
- Universitaire Ziekenhuis Antwerpen (Edegem)
- UZ Gent (Ghent)
- GHDC (Gilly)
- Jessa Ziekenhuis (Hasselt)
- UZ Brussel (Jette)
- UZ Leuven (Leuven)
- CHU Liège Sart Tilman (Liège)
- CHU UCL Namur (Namur)
- and 2 more in Belgium
How to use this
Talk to your care team first. They know your history and can tell you whether this trial is worth your time.
Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.
This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.