Testing engineered immune cells for H3K27M diffuse midline glioma and DIPG

Official title: H3K27M-specific Immune Effector Cells Targeting DMG/DIPG

Status: Not yet recruiting. It has not opened yet. Ask your care team to watch for it if it looks like a fit.

The trial team last updated this record on .

The short version

This study tests immune cells built to target a tumor change called H3K27M.

Read our full plain-language summary

What the trial team says

The purpose of this study is to assess the feasibility, safety and efficacy of H3K27M-specific engineered immune effector (EIE) therapy in patients with high-risk, H3K27M-positive diffuse midline glioma/diffuse intrinsic pontine glioma. Another goal of the study is to learn more about the function of the anti-H3K27M EIE cells and their persistency in patients.

From the trial's own listing on ClinicalTrials.gov.

Key facts

Registry number
NCT07501156
Stage of testing
Phase 1/Phase 2
Conditions studied
Diffuse Midline Glioma or Diffuse Intrinsic Pontine Glioma

Where it is running

This trial lists 1 site.

How to use this

Talk to your care team first. They know your history and can tell you whether this trial is worth your time.

Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.

See the full listing on ClinicalTrials.gov

This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.