Chemotherapy before radiation for newly diagnosed high-grade glioma
Official title: Pre-Radiation Chemotherapy for Newly Diagnosed High-Grade Glioma.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on .
The short version
This trial tests giving chemotherapy before radiation in newly diagnosed high-grade glioma: A tumor that starts in the glial cells. Those are the support cells of the brain and spinal cord. Gliomas are given a grade from 1 to 4. The grade says how the tumor is expected to act. See the glossary.
Read our full plain-language summary
What the trial team says
Better treatments are needed for high-grade gliomas (HGG), and new ways of treating this disease should be tested. The investigators want to see if giving medicine before radiation works well. After radiation, MRI scans can be harder to understand because radiation changes how the brain looks on the scan. If new medicines are given before radiation, the scans are easier to read. First, the investigators need to find out if giving chemotherapy early works using a drug we already know can treat gliomas. The investigators will start with temozolomide, which is the only chemotherapy approved by the FDA for HGG. If this approach is successful, the investigators can then test new drugs using this screening method.
Key facts
- Registry number
- NCT07439172
- Stage of testing
- Phase 2
- Conditions studied
- High Grade Gliomas, Glioblastoma, Astrocytoma, Oligodendroglioma
Where it is running
This trial lists 1 site.
-
New Jersey
- Cooper University HealthCare (Camden)
How to use this
Talk to your care team first. They know your history and can tell you whether this trial is worth your time.
Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.
This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.