A study of the drug ACT001 for DIPG and H3K27-altered high grade glioma
Official title: ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on .
The short version
This study is testing a drug called ACT001 in people with certain brain tumors.
Read our full plain-language summary
What the trial team says
This is a Phase II open-label study to investigate the safety and efficacy of ACT001 in patients with DIPG and H3K27-altered HGG.
Key facts
- Registry number
- NCT06838676
- Stage of testing
- Phase 2
- Conditions studied
- Diffuse Intrinsic Pontine Gliomas (DIPG), Progressive DIPG, Refractory DIPG, Recurrent DIPG, H3K27-altered High Grade Glioma
Where it is running
This trial lists 20 sites.
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Baden-Wurttemberg
- Hopp Children's Cancer Center at NCT Heidelberg (KiTZ) (Heidelberg)
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Colorado
- Children's Hospital Colorado (Aurora)
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District of Columbia
- Children's National Medical Center (Washington D.C.)
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Florida
- Nicklaus Children's Hospital (Miami)
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Georgia
- Emory University/Children's Healthcare of Atlanta (Atlanta)
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Grafton
- Starship Children's Hospital (Auckland)
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Michigan
- C.S. Mott Children's Hospital (Ann Arbor)
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Missouri
- St. Louis Children's Hospital (St Louis)
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New South Wales
- Sydney Children's Hospital (Randwick)
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North Carolina
- Duke University Medical Center (Durham)
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Ohio
- Cincinnati Children's Hospital (Cincinnati)
- Nationwide Children's Hospital (Columbus)
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Ontario
- The Hospital for Sick Children (SickKids) (Toronto)
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Pennsylvania
- Children's Hospital of Philidelphia (Philidelphia)
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Quebec
- Montreal Children's Hospital (Montreal)
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Queensland
- Queensland Children's Hospital (South Brisbane)
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Texas
- Texas Children's Hospital (Houston)
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Victoria
- Royal Children's Hospital (Melbourne)
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Washington
- Seattle Children's Hospital (Seattle)
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Western Australia
- Perth Children's Hospital (Perth)
How to use this
Talk to your care team first. They know your history and can tell you whether this trial is worth your time.
Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.
This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.