Arginine with whole brain radiation for cancer that has spread to the brain
Official title: Arginine and Whole Brain Radiation Therapy for the Treatment of Patients With Brain Metastases
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on .
The short version
This study is testing how to safely give arginine along with whole-brain radiation: Radiation given to the whole brain, rather than aimed at one spot. It is used when there are too many tumors to aim at one at a time. See the glossary.
Read our full plain-language summary
What the trial team says
This early phase I trial evaluates different administration techniques (oral or intravenous) for arginine and tests the safety of giving arginine with whole brain radiation therapy in patients who have cancer that has spread from where it first started (primary site) to the brain (brain metastases). Arginine is an essential amino acid. Amino acids are the molecules that join together to form proteins in the body. Arginine supplementation has been shown to improve how brain metastases respond to radiation therapy. The optimal dosing of arginine for this purpose has not been determined. This study measures the level of arginine in the blood with oral and intravenous dosing at specific time intervals before and after drug administration to determine the best dosing strategy.
Key facts
- Registry number
- NCT06328686
- Stage of testing
- Early phase 1
- Conditions studied
- Metastatic Malignant Neoplasm in the Brain, Metastatic Malignant Solid Neoplasm
Where it is running
This trial lists 1 site.
-
Georgia
- Emory University Hospital/Winship Cancer Institute (Atlanta)
How to use this
Talk to your care team first. They know your history and can tell you whether this trial is worth your time.
Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.
This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.