Testing extra brain scans to read changes after glioblastoma treatment
Official title: Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on .
The short version
This study tests if extra scans can tell tumor growth apart from treatment effects.
Read our full plain-language summary
What the trial team says
This phase II trial studies whether different imaging techniques can provide additional and more accurate information than the usual approach for assessing the activity of tumors in patients with newly diagnosed glioblastoma. The usual approach for this currently is magnetic resonance imaging (MRI). This study is trying to learn more about the meaning of changes in MRI scans after treatment, as while the appearance of some of these changes may reflect progressing tumor, some may be due the treatment. Dynamic susceptibility contrast (DSC)-MRIs, along with positron emission tomography (PET) and/or magnetic resonance (MR) spectroscopy, may help doctors tell which changes are a reflection of the treatment and which changes may be due to progressing tumor.
Key facts
- Registry number
- NCT06319027
- Stage of testing
- Phase 2
- Conditions studied
- Glioblastoma, IDH-Wildtype
Where it is running
This trial lists 18 sites.
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Alabama
- University of Alabama at Birmingham Cancer Center (Birmingham)
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California
- Cedars-Sinai Medical Center (Los Angeles)
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Florida
- Baptist MD Anderson Cancer Center (Jacksonville)
- Moffitt Cancer Center (Tampa)
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Georgia
- Emory University Hospital/Winship Cancer Institute (Atlanta)
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Michigan
- University of Michigan Rogel Cancer Center (Ann Arbor)
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North Carolina
- Carolinas Medical Center/Levine Cancer Institute (Charlotte)
- Duke University Medical Center (Durham)
- Wake Forest University Health Sciences (Winston-Salem)
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Rhode Island
- Rhode Island Hospital (Providence)
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West Virginia
- Edwards Comprehensive Cancer Center (Huntington)
- West Virginia University Healthcare (Morgantown)
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Wisconsin
- University of Wisconsin Carbone Cancer Center - Eastpark Medical Center (Madison)
- University of Wisconsin Carbone Cancer Center - University Hospital (Madison)
- Froedtert Menomonee Falls Hospital (Menomonee Falls)
- Medical College of Wisconsin (Milwaukee)
- Drexel Town Square Health Center (Oak Creek)
- Froedtert West Bend Hospital/Kraemer Cancer Center (West Bend)
How to use this
Talk to your care team first. They know your history and can tell you whether this trial is worth your time.
Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.
This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.