A study of how radiation changes brain networks in children with brain tumors
Official title: Radiation Induced Alterations in Resting State Brain Networks in Pediatric Brain Tumor Patients
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on .
The short version
This study uses brain scans to look at how radiation treatment changes the way a child's brain works.
Read our full plain-language summary
What the trial team says
With modern therapy, the survival rate for pediatric brain tumor patients has significantly improved, with over 70% of patients surviving their disease. However, this progress often comes at the cost of substantial morbidity, with cognitive deficits being the primary obstacle to independent living. Robust predictors of cognitive decline and a comprehensive understanding of the underlying mechanisms of cognitive injury remain elusive. This study will prospectively investigate alterations in brain resting state networks following radiation therapy using functional imaging. The hypothesis is that radiation therapy leads to dose-dependent alterations in functional connectivity in the networks associated with higher level cognition, ultimately leading to cognitive decline.
Key facts
- Registry number
- NCT06185686
- Conditions studied
- Brain Tumor, Primary
Where it is running
This trial lists 1 site.
-
Missouri
- Washington University School of Medicine/Saint Louis Children's Hospital (St Louis)
How to use this
Talk to your care team first. They know your history and can tell you whether this trial is worth your time.
Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.
This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.