Gene testing of new brain tumors in young people
Official title: Targeted Pediatric High-Grade Glioma Therapy
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on .
The short version
This study looks at the genes in a child's or young adult's newly found high-grade glioma: A tumor that starts in the glial cells. Those are the support cells of the brain and spinal cord. Gliomas are given a grade from 1 to 4. The grade says how the tumor is expected to act. See the glossary.
Read our full plain-language summary
What the trial team says
The goal of this study is to perform genetic sequencing on brain tumors from children, adolescents, and young adult patients who have been newly diagnosed with a high-grade glioma. This molecular profiling will decide if patients are eligible to participate in a subsequent treatment-based clinical trial based on the genetic alterations identified in their tumor.
Key facts
- Registry number
- NCT05839379
- Conditions studied
- High Grade Glioma, Diffuse Intrinsic Pontine Glioma, Anaplastic Astrocytoma, Glioblastoma, Glioblastoma Multiforme, Diffuse Midline Glioma, H3 K27M-Mutant, Metastatic Brain Tumor, WHO Grade III Glioma, WHO Grade IV Glioma
Where it is running
This trial lists 22 sites.
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Baden-Wurttemberg
- Hopp Children's Cancer Center at NCT Heidelberg (KiTZ) (Heidelberg)
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Colorado
- Children's Hospital Colorado (Aurora)
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District of Columbia
- Children's National Medical Center (Washington D.C.)
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Florida
- University of Miami (Miami)
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Grafton
- Starship Children's Hospital (Auckland)
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Illinois
- Ann & Robert H. Lurie Children's Hospital of Chicago (Chicago)
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Massachusetts
- Dana-Farber Cancer Institute (Boston)
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Michigan
- C.S. Mott Children's Hospital (Ann Arbor)
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Netherlands
- Princess Máxima Center (Utrecht)
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New South Wales
- Sydney Children's Hospital (Randwick)
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North Carolina
- Duke University Health System (Durham)
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Ohio
- Cincinnati Children's Hospital Medical Center (Cincinnati)
- Nationwide Children's Hospital (Columbus)
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Ontario
- The Hospital for Sick Children (SickKids) (Toronto)
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Pennsylvania
- Children's Hospital of Philadelphia (Philadelphia)
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Quebec
- Montreal Children's Hospital (Montreal)
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Queensland
- Queensland Children's Hospital (South Brisbane)
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Texas
- Texas Children's Hospital (Houston)
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United Kingdom
- Great Ormond Street Hospital (London)
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Victoria
- Royal Children's Hospital (Melbourne)
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Washington
- Seattle Children's Hospital (Seattle)
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Western Australia
- Perth Children's Hospital (Perth)
How to use this
Talk to your care team first. They know your history and can tell you whether this trial is worth your time.
Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.
This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.