Comparing two ways to give focused radiation to brain tumors that spread from other cancers
Official title: SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on .
The short version
This study compares one dose of focused radiation with the same treatment split into more than one dose.
Read our full plain-language summary
What the trial team says
This phase II trial compares the effect of single fraction stereotactic radiosurgery to fractionated stereotactic radiosurgery for the treatment of patients with cancer that has spread to the brain (metastatic brain disease). Stereotactic radiosurgery (SRS) is a form of radiation therapy that focuses high-power energy on a small area of the body. This trial is being done to determine if single (one) fraction stereotactic radiosurgery is better than fractionated stereotactic radiosurgery or vice versa in controlling tumor and side effects in patients with tumors that have spread to the brain.
Key facts
- Registry number
- NCT05222620
- Stage of testing
- Phase 2
- Conditions studied
- Metastatic Malignant Neoplasm in the Brain, Metastatic Malignant Solid Neoplasm
Where it is running
This trial lists 7 sites.
-
Arizona
- Mayo Clinic in Arizona (Scottsdale)
-
Florida
- Mayo Clinic in Florida (Jacksonville)
-
Minnesota
- Mayo Clinic Health System in Albert Lea (Albert Lea)
- Mayo Clinic Health Systems-Mankato (Mankato)
- Mayo Clinic in Rochester (Rochester)
-
Wisconsin
- Mayo Clinic Health System-Eau Claire Clinic (Eau Claire)
- Mayo Clinic Health System-Franciscan Healthcare (La Crosse)
How to use this
Talk to your care team first. They know your history and can tell you whether this trial is worth your time.
Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.
This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.