Three Drugs Given Together for Glioma That Came Back or Did Not Respond
Official title: Pembrolizumab, Olaparib, and Temozolomide for People With Glioma
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on .
The short version
This study is testing whether three drugs given together can help people whose glioma: A tumor that starts in the glial cells, the support cells of the brain and spinal cord. Gliomas are graded 1 to 4 by how fast they tend to grow. See the glossary came back or did not get better with earlier treatment.
Read our full plain-language summary
What the trial team says
This study will test the safety and effectiveness of a combination of pembrolizumab, olaparib, and temozolomide to see how well these drugs work when given together in people with a glioma that either did not respond to previous treatment or came back after treatment.
Key facts
- Registry number
- NCT05188508
- Stage of testing
- Phase 2
- Conditions studied
- Glioma
Where it is running
This trial lists 10 sites.
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Connecticut
- Hartford Healthcare Alliance (Data Collection Only) (Hartford)
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Florida
- BAPTIST ALLIANCE - MCI (Data Collection Only) (Miami)
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New Jersey
- Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities) (Basking Ridge)
- Memorial Sloan Kettering Monmouth (Limited Protocol Activities) (Middletown)
- Memorial Sloan Kettering Bergen (Limited Protocol Activities) (Montvale)
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New York
- Memorial Sloan Kettering Suffolk -Commack (Limited Protocol Activities) (Commack)
- Memorial Sloan Kettering Westchester (Limited Protocol Activities) (Harrison)
- Memorial Sloan Kettering Cancer Center (All Protocol Activities) (New York)
- Memorial Sloan Kettering Nassau (Limited Protocol Activities) (Uniondale)
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Pennsylvania
- Lehigh Valley Health Network (Data Collection Only) (Allentown)
How to use this
Talk to your care team first. They know your history and can tell you whether this trial is worth your time.
Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.
This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.