Deferoxamine put into the spinal fluid for people whose cancer has spread to the lining around the brain and spinal cord
Official title: A Study of Deferoxamine (DFO) in People With Leptomeningeal Metastasis
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on .
The short version
This study is testing whether a drug called deferoxamine is safe when it is put straight into the fluid around the brain and spinal cord.
Read our full plain-language summary
What the trial team says
The researchers are doing this study to find out whether deferoxamine (DFO) given intrathecally (directly into the CSF) is a safe treatment for people with leptomeningeal metastasis from solid tumor cancer. The researchers will test different doses of DFO to find the highest dose that causes few or mild side effects. When the dose is found, they will test it in future participants to see whether DFO is a safe and effective treatment for people with leptomeningeal metastasis from solid tumor malignancies. They are also doing this study to see how the body absorbs, distributes, gets rid of, and responds to DFO.
Key facts
- Registry number
- NCT05184816
- Stage of testing
- Phase 1
- Conditions studied
- Leptomeningeal Metastases
Where it is running
This trial lists 7 sites.
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New Jersey
- Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities) (Basking Ridge)
- Memorial Sloan Kettering Monmouth (Limited Protocol Activities) (Middletown)
- Memorial Sloan Kettering Bergen (Limited Protocol Activities) (Montvale)
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New York
- Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities) (Commack)
- Memorial Sloan Kettering Westchester (Limited Protocol Activities) (Harrison)
- Memorial Sloan Kettering Cancer Center (All Protocol Activities) (New York)
- Memorial Sloan Kettering Nassau (Limited Protocol Activities) (Uniondale)
How to use this
Talk to your care team first. They know your history and can tell you whether this trial is worth your time.
Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.
This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.