Testing a treatment plan built for each person's tumor in children and young adults whose medulloblastoma or ependymoma has come back
Official title: Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and Ependymoma
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on .
The short version
This study tests whether a care team can build a treatment plan that fits one person's own tumor.
Read our full plain-language summary
What the trial team says
The current study will use a new treatment approach based on the molecular characteristics of each participant's tumor. The study will test the feasibility in the pilot phase of performing real-time drug screening on tissue taken during surgery in patients with relapsed medulloblastoma or ependymoma and of having a specialized tumor board assign a treatment plan based on the results of this screening and genomic sequencing. The aim of this trial is to allow every child and young adult with relapsed medulloblastoma and ependymoma to receive the most effective and least toxic therapies currently available and will pave the way for improved understanding and treatment of these tumors in the future. Moreover, if successful, it could serve as a paradigm for personalized medicine programs for other types of cancer.
Key facts
- Registry number
- NCT05057702
- Stage of testing
- Not applicable
- Conditions studied
- Medulloblastoma, Medulloblastoma, Childhood, Medulloblastoma Recurrent, Ependymoma, Ependymoma Malignant, Ependymoma of Brain
Where it is running
This trial lists 9 sites.
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California
- Children's Hospital of Los Angeles (Los Angeles)
- Rady Children's Hospital (San Diego)
- University of California, San Francisco (San Francisco)
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District of Columbia
- Children's National Hospital (Washington D.C.)
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Minnesota
- Children's Minnesota (Minneapolis)
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Missouri
- St. Louis Children's Hospital / Washington University in St. Louis (St Louis)
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New York
- New York University (New York)
- Columbia University Medical Center (New York)
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Pennsylvania
- Children's Hospital of Philadelphia (Philadelphia)
How to use this
Talk to your care team first. They know your history and can tell you whether this trial is worth your time.
Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.
This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.