Testing the drug mirdametinib for children and young adults with low-grade glioma

Official title: SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma

Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.

The trial team last updated this record on .

The short version

This study tests a drug called mirdametinib in young people with a brain tumor called low-grade glioma: A tumor that starts in the glial cells. Those are the support cells of the brain and spinal cord. Gliomas are given a grade from 1 to 4. The grade says how the tumor is expected to act. See the glossary.

Read our full plain-language summary

What the trial team says

This is an open-label, multi-center, Phase 1/2 study of the brain-penetrant MEK inhibitor, mirdametinib (PD-0325901), in patients with pediatric low-grade glioma (pLGG).

From the trial's own listing on ClinicalTrials.gov.

Key facts

Registry number
NCT04923126
Stage of testing
Phase 1/Phase 2
Conditions studied
Low-Grade Glioma, Recurrent Low-Grade Glioma, Progressive Low-Grade Glioma

Where it is running

This trial lists 1 site.

How to use this

Talk to your care team first. They know your history and can tell you whether this trial is worth your time.

Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.

See the full listing on ClinicalTrials.gov

This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.