Testing palbociclib alone and with pembrolizumab for cancer that has spread to the brain or spinal cord

Official title: Palbociclib and Pembrolizumab In Central Nervous System Metastases

Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.

The trial team last updated this record on .

The short version

This study is testing two drugs, one by itself and the two together, in people whose cancer has spread to the brain or spinal cord and has come back.

Read our full plain-language summary

What the trial team says

This research study is studying This research study is studying the efficacy and safety of the following study drugs as a possible treatment for recurrent central nervous system (CNS) metastases: * Palbociclib alone (Cohort 1) * The combination of palbociclib and pembrolizumab (Cohort 2) Pfizer and Merck, pharmaceutical companies, are supporting this research study by providing the study drugs as well as funding for research activities.

From the trial's own listing on ClinicalTrials.gov.

Key facts

Registry number
NCT02896335
Stage of testing
Phase 2
Conditions studied
Metastatic Malignant Neoplasm to Brain, Recurrent Brain Metastases, Progressive Brain Metastases

Where it is running

This trial lists 2 sites.

How to use this

Talk to your care team first. They know your history and can tell you whether this trial is worth your time.

Joining a trial is always your choice. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you.

See the full listing on ClinicalTrials.gov

This page is built from the trial's listing on ClinicalTrials.gov, a service of the U.S. National Library of Medicine. That listing is the authority, and it may have changed since we last read it. We do not run this trial and we cannot enroll you in it.