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WP1066 with radiation for people newly diagnosed with glioblastoma

Original title: WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

How far along is this research?

This is a trial that is enrolling or has been updated. It is not a finding yet.

This is a middle stage trial, so the drug is still being tested in people.

Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.

The trial team last updated this record on . Always check the trial page for the latest.

The short version

This study is testing whether adding a drug called WP1066 to radiation helps people with a new glioblastoma: The fastest-growing type of glioma (grade 4). Treatment usually starts soon after diagnosis: surgery first, then radiation and chemotherapy. See the glossary diagnosis.

Who this trial is for. This trial is for people who have just been diagnosed with glioblastoma: The fastest-growing type of glioma (grade 4). Treatment usually starts soon after diagnosis: surgery first, then radiation and chemotherapy. See the glossary. It tests a drug called WP1066 given together with radiation therapy.

Where it stands. There are no results from this trial. The study is measuring how well WP1066 and radiation work together against the tumor. The hope is that the pair may slow tumor growth and help people live longer. That has not been shown. The answer is not in yet.

What this means, and what it doesn't

What it could mean: glioblastoma: The fastest-growing type of glioma (grade 4). Treatment usually starts soon after diagnosis: surgery first, then radiation and chemotherapy. See the glossary is hard to treat, so researchers are trying more than one approach at once. WP1066 aims at a pathway called STAT3. STAT3 helps the tumor grow and helps it avoid the body's immune system. If you were recently diagnosed, you could ask your care team whether a trial like this is worth looking into for you.

What it doesn't mean: This does not mean WP1066 works. A trial is a test, not a proven treatment. Joining one is not a guarantee that it will help you. It is not a promise of a cure. Only the trial team can decide if someone can take part.

Source: ClinicalTrials.gov, July 22, 2026 · Read the original

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