What predicts meningioma shrinkage after stopping cyproterone acetate
Original title: Prediction of meningioma shrinkage after cyproterone acetate cessation.
How far along is this research?
- Lab cells
- Animals
- Review
- Tested in people
This was tested in people. That is the most reliable kind of research we share.
This was a look back at scans from people who were already treated, not a new treatment you can get.
The short version
Most of these tumors got smaller after patients stopped the drug.
What was studied. Doctors looked back at 137 meningiomas in 52 patients. Every tumor was found while the patient was taking cyproterone acetate, a hormone drug. The team measured tumor size on all the scans the patients had over time.
What they found. Most tumors shrank after the drug was stopped. 47% shrank down to a low size limit. 41% shrank to a higher size limit. 12% did not shrink at all. The most useful clues were how much tumor there was at the start and the patient's age. Checking the tumor size again at 3 months made the predictions much more accurate.
What this means, and what it doesn't
What it could mean: If you stop this drug, there is a good chance your tumor will shrink or settle. Your doctor may be able to give you a rough idea of what to expect, based on your tumor size and your age. A scan a few months after stopping can make that guess better.
What it doesn't mean: Stopping the drug is not a cure. It is not a promise that every tumor shrinks. Some tumors here did not respond. This was a look back at scans from patients who were already treated. It was not a trial of a new treatment. The prediction method is a research tool. It is not something you can ask for at a clinic today. It would need testing in other groups of patients first.
Source: PubMed, June 25, 2026 · Read the original
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