Testing whether pesticide exposure affects glioblastoma treatment
Original title: Impact of Pesticide Exposure on Survival and Tumor Aggressiveness in Patients With Glioblastoma: A Prospective Clinical Study
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
No phase is given for this study, so it is still an early question being tested in people.
Status: Not yet recruiting. It has not opened yet. Ask your care team to watch for it if it looks like a fit.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study looks at whether past pesticide exposure changes how a brain tumor responds to treatment.
Who this trial is for. This study is for adults over 18 with IDH gene change: A small change in a tumor's IDH gene. It is the first thing your team looks at when naming an adult glioma, and it can affect which treatments are offered. Your pathology report says whether your tumor has it. See the glossary wild-type glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary who are about to start treatment. It plans to include 120 people, and it will look at whether pesticide exposure is linked to how the tumor responds.
Where it stands. The trial has not reported results. People give urine, hair, and blood samples and fill out a questionnaire before treatment starts. Then their tumor response and survival status are tracked for about 3 years. The answer is not in yet.
What this means, and what it doesn't
What it could mean: If you have glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary and think you were around pesticides, this study is asking that exact question. Someone who fits could ask their care team about it. Taking part here means giving samples and answering questions, not getting a new treatment.
What it doesn't mean: A trial is a test, not a proven treatment. Joining one does not guarantee any benefit. It is not a promise of a cure. This study is looking for a link between pesticides and tumor response. It has not shown one.
Source: ClinicalTrials.gov, August 26, 2026 · Read the original
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