Testing ultrasound with a glowing dye during brain tumor surgery
Original title: Concurrent Fluorescence and Sonographically Guided Eradication of High-grade Gliomas and Metastases
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
No phase is listed for this study, so it is still being tested in people.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study tests if adding ultrasound in surgery helps doctors take out more tumor.
Who this trial is for. This trial is for people having surgery for a high grade glioma: A tumor that starts in the glial cells. Those are the support cells of the brain and spinal cord. Gliomas are given a grade from 1 to 4. The grade says how the tumor is expected to act. See the glossary or a tumor that spread to the brain, with the tumor in one half of the brain. It tests a dye called 5-ALA: A medicine you are given before some brain operations. The tumor soaks it up. Under a special light the tumor then glows, so the surgeon can see where it stops and healthy brain starts. See the glossary that makes tumor glow, used along with ultrasound pictures during surgery, compared with the glowing dye alone.
Where it stands. The trial is measuring how often surgeons are able to take out all of the tumor. It compares the two ways of guiding surgery. The trial has not reported results. The answer is not in yet.
What this means, and what it doesn't
What it could mean: If the added ultrasound helps, surgery may remove more of the tumor. Someone facing this kind of surgery could ask their care team about this trial.
What it doesn't mean: This does not mean the approach is proven. A trial is a test, not care your doctor can simply give you. Joining a trial is not a guarantee that it will help you. It is not a promise of a cure.
Source: ClinicalTrials.gov, October 16, 2026 · Read the original
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