Testing two new drugs after surgery for newly diagnosed glioblastoma
Original title: D2C7-IT and 2141-V11 in Newly Diagnosed GBM Patients
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This is an early test in people to check safety and see what the drugs do.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study tests two new drugs in adults just diagnosed with a brain tumor called glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary.
Who this trial is for. This trial is for adults newly diagnosed with glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary, a cancerous brain tumor. It tests two study drugs, D2C7-IT and 2141-V11, given after brain surgery, with later shots of 2141-V11 under the skin.
Where it stands. This trial has not reported results. It is checking how safe the two drugs are and how well they work. The answer is not in yet.
What this means, and what it doesn't
What it could mean: Someone newly diagnosed with glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary could ask their care team about this study. The team can say whether it fits their case. The drugs are still being tested and are not approved by the FDA.
What it doesn't mean: This does not mean these drugs work. A trial is a test, not a proven treatment. Being in one is not a guarantee of benefit. It is not a promise of a cure.
Source: ClinicalTrials.gov, October 16, 2026 · Read the original
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