Testing two drugs together after surgery for glioblastoma that came back
Original title: D2C7-IT + 2141-V11 Combination Post-resection in rGBM
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This is an early test in people, mostly to check safety.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study tests two drugs given together in people whose glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary has returned.
Who this trial is for. This trial is for people whose glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary came back and was taken out by surgery. It tests two drugs, D2C7-IT and 2141-V11, placed into the brain through a thin tube. After that, 2141-V11 is also given as shots under the skin in the neck.
Where it stands. The trial is checking how safe this combination is and how well it works. The answer is not in yet. The trial has not reported results.
What this means, and what it doesn't
What it could mean: Someone whose glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary has come back and who had surgery might fit this study. If that sounds like you, you can ask your care team about it. They can help you see if it is worth looking into.
What it doesn't mean: This does not mean the drugs work. A trial is a test, not a proven treatment. Joining one is not a promise that it will help you. It is not a cure.
Source: ClinicalTrials.gov, October 21, 2026 · Read the original
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