Testing two drugs after focused radiation for lymphoma in the brain and spinal cord
Original title: Loncastuximab Tesirine and Rituximab Following Stereotactic Radiosurgery in Patients With Central Nervous System Lymphomas (SOLAR)
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This is an early first test in people to see if the treatment is safe.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study is testing whether two drugs given after focused radiation are safe and helpful for people with lymphoma in the brain or spinal cord.
Who this trial is for. This trial is for people who have lymphoma in the central nervous system. That means the brain and spinal cord. People first get a focused kind of radiation called stereotactic radiosurgery. Then they get two drugs, loncastuximab tesirine and rituximab.
Where it stands. This trial has not reported results. It is looking at whether the two drugs are safe after this radiation. It is also looking at how well they work. Those answers are not in yet.
What this means, and what it doesn't
What it could mean: Nothing here is proven yet. If you have lymphoma in the brain or spinal cord, you could ask your care team about this trial. They can help you think about whether it fits your situation. Whether you can join is up to the trial team.
What it doesn't mean: This does not mean the drugs work. A trial is a test, not a proven treatment. Being in a trial is not a guarantee that it will help you. It is not a promise of a cure.
Source: ClinicalTrials.gov, August 10, 2026 · Read the original
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