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Testing the Cerebraca Wafer With Temozolomide for Glioblastoma That Has Come Back

Original title: Comparison of Cerebraca Wafer Plus Temozolomide Versus Temozolomide Alone in Recurrent Glioblastoma

How far along is this research?

This is a trial that is enrolling or has been updated. It is not a finding yet.

This is a larger test in people, but the wafer is not approved care yet.

Status: Not yet recruiting. It has not opened yet. Ask your care team to watch for it if it looks like a fit.

The trial team last updated this record on . Always check the trial page for the latest.

The short version

Doctors are testing whether adding a wafer at surgery helps people whose glioblastoma: A glioma that is given grade 4, the highest grade. It grows fast. Treatment usually starts soon after it is found. It often means surgery, then radiation and chemotherapy. See the glossary has come back.

Who this trial is for. This trial is for people whose glioblastoma: A glioma that is given grade 4, the highest grade. It grows fast. Treatment usually starts soon after it is found. It often means surgery, then radiation and chemotherapy. See the glossary has come back. It compares the Cerebraca Wafer used with surgery, then the usual drug temozolomide: A chemotherapy taken as a capsule, used for some brain tumors. Your team checks your blood counts while you are on it. See the glossary, against temozolomide alone.

Where it stands. This trial has not reported any results. It is set up to see how well the wafer works. People will be put into groups by chance. Everyone will know which treatment they get. The study is planned at more than one medical center.

What this means, and what it doesn't

What it could mean: If the wafer helps, it could one day give people another choice when glioblastoma: A glioma that is given grade 4, the highest grade. It grows fast. Treatment usually starts soon after it is found. It often means surgery, then radiation and chemotherapy. See the glossary returns. If your glioblastoma has come back, you could ask your care team whether this trial might fit you.

What it doesn't mean: This trial is a test, not a proven treatment. No one knows yet if the wafer helps. Being in a trial does not mean you will benefit. This is not a cure. Whether someone can join is decided by the trial team.

Source: ClinicalTrials.gov, September 10, 2026 · Read the original

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