Testing tarlatamab for brain tumors that spread from small cell lung cancer
Original title: Tarlatamab for SCLC Brain Metastases
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This is a middle stage trial that is still testing whether the drug helps.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This trial is testing a drug called tarlatamab in people whose small cell lung cancer has spread to the brain.
Who this trial is for. This trial is for people with small cell lung cancer that has spread to the brain. The brain spots are active but are not causing symptoms. Everyone in the trial gets tarlatamab. There is no comparison group.
Where it stands. The trial is measuring how well tarlatamab works on the tumors in the brain. It has not reported results. The answer is not in yet.
What this means, and what it doesn't
What it could mean: There is not yet an answer about whether this drug helps brain tumors from small cell lung cancer. Someone whose situation sounds like this could ask their care team about the trial. The care team can explain if it makes sense for them.
What it doesn't mean: This does not mean tarlatamab works for brain tumors from small cell lung cancer. A trial is a test, not a proven treatment. Joining one is not a guarantee that it will help you. It is not a promise of a cure.
Source: ClinicalTrials.gov, July 31, 2026 · Read the original
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