Testing palbociclib alone and with pembrolizumab for cancer that has spread to the brain or spinal cord
Original title: Palbociclib and Pembrolizumab In Central Nervous System Metastases
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This is a middle stage test in people, so the drugs are still being studied.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study is testing two drugs, one by itself and the two together, in people whose cancer has spread to the brain or spinal cord and has come back.
Who this trial is for. This trial is for people with cancer that has spread to the central nervous system, which means the brain and spinal cord, and has come back. One group takes palbociclib by itself. Another group takes palbociclib along with pembrolizumab.
Where it stands. There are no results yet. The trial is checking how well these drugs work and how safe they are. That answer is not in.
What this means, and what it doesn't
What it could mean: This is one more thing being looked at for cancer that has spread to the brain or spinal cord. If this sounds like your situation, you can ask your care team about it. They can help you decide if it is worth looking into. Whether someone can join is decided by the trial team.
What it doesn't mean: This does not mean these drugs are a proven treatment. A trial is a test, and the answers are not known yet. Being in a trial is not a guarantee that it will help you. It is not a promise of a cure.
Source: ClinicalTrials.gov, July 21, 2026 · Read the original
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