Testing metformin and a wearable watch to protect thinking after brain radiation
Original title: Remote Cognitive Assessment and Wearable Device While Assessing the Impact of Metformin in Patients With History of Cranial Radiation Therapy
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This is a middle stage study, so it is still being tested in people.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study is testing whether a diabetes drug and a wearable watch can help protect thinking skills in people who get radiation to the head.
Who this trial is for. This trial is for people who are getting radiation to the skull, or who have had it in the past. It is testing metformin, a wearable watch device, and doing check-ins from home instead of in the clinic.
Where it stands. This trial has not reported results. It is looking at whether patient care can be done remotely, and it is comparing people who take metformin with people who do not. Thinking skills are checked with Mayo Test Drive, a website people can use on their own from home. The answers are not in yet.
What this means, and what it doesn't
What it could mean: Radiation to the head can make it harder to think, learn, and remember. This trial is trying to find out if metformin and a wearable device can help with that, and if some of the care can be done from home. If this sounds like it fits your situation, you can ask your care team about it.
What it doesn't mean: This does not mean metformin or a wearable watch protects thinking after radiation. A trial is a test, not a proven treatment. Being in a trial is not a guarantee that it will help you. It is not a promise of a cure.
Source: ClinicalTrials.gov, July 16, 2026 · Read the original
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