Testing immune cells made from a child's own brain tumor
Original title: Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT)
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This is an early first test in people to check safety.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
Doctors are testing immune cells built to match a child's own brain tumor.
Who this trial is for. This trial is for children with certain brain tumors. One group is children less than 5 years of age with embryonal brain tumors, after their usual treatment. The other group is children whose ependymoma has come back. It tests immune cells made to target markers found in the child's own tumor tissue.
Where it stands. This trial has not reported results. It is checking whether the cells can be made and whether they are safe. It is also measuring effects on the tumor and the immune system. Those answers are not in yet.
What this means, and what it doesn't
What it could mean: We do not know yet if this helps. A family whose child might fit could ask their care team about it. The trial team decides who can join.
What it doesn't mean: This does not mean the treatment works. A trial is a test, not proven care. Joining one is not a promise of benefit. It is not a cure.
Source: ClinicalTrials.gov, October 13, 2026 · Read the original
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