Testing desmopressin during surgery for hard-to-treat tumors near the pituitary gland
Original title: Randomized Controlled Clinical Study on the Prophylactic Intraoperative Use of Desmopressin in Complex Sellar Region Tumors
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This is a late-stage study in people.
Status: Enrolling by invitation. It is only taking people the trial team invites. You cannot sign up for this one directly.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This trial is testing whether a drug given during surgery can keep salt levels in the blood from climbing too high.
Who this trial is for. This trial is for people having surgery for complex tumors in the sellar region, the area around the pituitary gland. It is testing a low dose of desmopressin, also called dDAVP, given slowly through a vein during the operation.
Where it stands. The trial has not reported results. It is measuring how often blood sodium rises too high during surgery or in the first 24 hours after. It is also looking at how safe the drug is. The answer is not in yet.
What this means, and what it doesn't
What it could mean: Surgery on these tumors can upset how the body holds on to water. That can push blood sodium too high, which can cause serious problems. Right now there is not enough proof to give this drug to everyone during surgery. This trial is asking whether giving it ahead of time helps. Someone facing this kind of surgery could ask their care team about it.
What it doesn't mean: This does not mean the drug works. A trial is a test, not a proven treatment. Being in a trial is not a guarantee that it will help you. It is not a promise of a cure. It also does not mean anyone can join. That is decided by the trial team, not by us.
Source: ClinicalTrials.gov, July 17, 2026 · Read the original
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