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Testing a sleep medicine for people having brain tumor surgery

Original title: Lemborexant on Perioperative Sleep Quality in Patients With Brain Tumor Undergoing Surgery

How far along is this research?

This is a trial that is enrolling or has been updated. It is not a finding yet.

This is a middle stage trial, so the medicine is still being tested in people.

Status: Not yet recruiting. It has not opened yet. Ask your care team to watch for it if it looks like a fit.

The trial team last updated this record on . Always check the trial page for the latest.

The short version

This trial asks if a sleep medicine helps people sleep better around brain surgery.

Who this trial is for. Adults with a brain tumor who have surgery planned may join. People take either the sleep medicine lemborexant or a placebo the night before surgery. A placebo is a pill with no medicine in it. Which one you get is picked at random.

Where it stands. This trial has not reported results. The team plans to measure sleep quality, waking up from anesthesia, pain, and recovery after surgery. The answers are not in yet.

What this means, and what it doesn't

What it could mean: Sleep is often hard in the days around brain surgery. This trial asks if one medicine can help with that. Someone who fits the picture above could ask their care team about it.

What it doesn't mean: This does not mean the medicine works. A trial is a test, not a proven treatment. Joining one is not a promise that you will feel better. Some people get a placebo instead of the medicine. This is not a cure.

Source: ClinicalTrials.gov, October 29, 2026 · Read the original

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