Testing a new drug called GLIX1 in adults whose high grade glioma has come back or grown
Original title: A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This is an early safety test in people to find the right dose.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study is testing how safe the drug GLIX1 is, and what dose to use, in adults whose high grade glioma: A tumor that starts in the glial cells, the support cells of the brain and spinal cord. Gliomas are graded 1 to 4 by how fast they tend to grow. See the glossary has come back or kept growing.
Who this trial is for. This trial is for adults with a high grade glioma: A tumor that starts in the glial cells, the support cells of the brain and spinal cord. Gliomas are graded 1 to 4 by how fast they tend to grow. See the glossary that grew during earlier treatment or came back after it. It tests a drug called GLIX1, given on its own as capsules taken every day. The study starts with lower doses and works up to find the right dose.
Where it stands. The trial has not reported results. It is watching how safe GLIX1 is, how well people handle it, what the tumor does, and how the body handles the drug. Those answers are not in yet.
What this means, and what it doesn't
What it could mean: If your high grade glioma: A tumor that starts in the glial cells, the support cells of the brain and spinal cord. Gliomas are graded 1 to 4 by how fast they tend to grow. See the glossary has come back or grown after treatment, this is a study you could ask your care team about. They know your case and can tell you whether it is worth looking into.
What it doesn't mean: This does not mean GLIX1 works. A trial is a test, not a proven treatment. Being in one is not a guarantee that it will help you. It is not a promise of a cure.
Source: ClinicalTrials.gov, July 30, 2026 · Read the original
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