Testing a more detailed brain scan to guide Optune patch placement in glioblastoma
Original title: WBSI Guided Personalized Delivery of TTFields
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This study does not list a phase, so we treat it as an early test in people.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study is testing whether a more detailed brain scan can help place the tumor treating fields: A treatment that makes it harder for tumor cells to divide. It uses electric fields that switch back and forth. The fields come from pads on the scalp. A box you carry drives them. The box is often called Optune. See the glossary patches better.
Who this trial is for. This study is for people with glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary who are about to start tumor treating fields: A treatment that makes it harder for tumor cells to divide. It uses electric fields that switch back and forth. The fields come from pads on the scalp. A box you carry drives them. The box is often called Optune. See the glossary as part of their regular care. Optune uses tumor treating fields, which are electrical fields sent through patches on the head. Some people in the study get the patches placed using standard mapping from a regular contrast MRI. Others get placement guided by more detailed scans, including whole brain spectroscopy, which looks at the chemistry of brain tissue to show more of where tumor cells may have spread.
Where it stands. The study has not reported results. The team wants to see if the more detailed mapping delivers more of the treatment to the tumor. They are looking at whether the tumor comes back in the same area, how long people live, and how people feel day to day. The answers are not in yet.
What this means, and what it doesn't
What it could mean: If this works, it could mean a better way to decide where the tumor treating fields: A treatment that makes it harder for tumor cells to divide. It uses electric fields that switch back and forth. The fields come from pads on the scalp. A box you carry drives them. The box is often called Optune. See the glossary patches go. Right now that is only a question the study is asking. If you have glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary and are starting Optune, you could ask your care team whether a study like this fits your situation.
What it doesn't mean: This does not mean the detailed mapping is proven to work. A trial is a test, not a treatment your doctor can give you as standard care. Joining a study is not a guarantee that it will help you. It is not a promise of a cure.
Source: ClinicalTrials.gov, August 6, 2026 · Read the original
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