Testing a mix of drugs and a tumor vaccine for glioma that is still there after treatment
Original title: Medication Combinations of Dasatinib, Quercetin, Fisetin, Temozolomide, LMP744, and Autologous TLPO Vaccine for the Treatment of Previously Treated Glioma With Residual Disease
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This is an early first test in people to check how safe it is.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study tests if a drug and vaccine mix is safe for leftover glioma: A tumor that starts in the glial cells, the support cells of the brain and spinal cord. Gliomas are given a grade from 1 to 4 describing how the tumor is expected to behave. See the glossary.
Who this trial is for. This trial is for people with glioma: A tumor that starts in the glial cells, the support cells of the brain and spinal cord. Gliomas are given a grade from 1 to 4 describing how the tumor is expected to behave. See the glossary who have had treatment before, and who still have tumor cells left. It tests dasatinib, quercetin, fisetin, temozolomide: A chemotherapy taken as a capsule, used for some brain tumors. Your team checks your blood counts while you are on it. See the glossary, LMP744, and a vaccine made from the person's own tumor, given together in combinations.
Where it stands. The trial has not reported results. It is checking how safe these combinations are and what side effects they cause. It is also checking how well they work. Those answers are not in yet.
What this means, and what it doesn't
What it could mean: Right now this is a study, not care your own doctor can give you. If this sounds like your situation, you can ask your care team about it. They can help you think it through.
What it doesn't mean: This does not mean these drugs and the vaccine work. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you. It is not a cure.
Source: ClinicalTrials.gov, October 1, 2026 · Read the original
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