Testing a lab method that checks how brain and spinal cord tumor tissue reacts to drugs
Original title: Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This study is testing a new lab method, and it is not care you can get from your own doctor yet.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study tests a lab method that looks at how tumor tissue reacts to different medicines.
Who this trial is for. This study is for people aged 15 years and older whose brain or spinal cord tumor has come back. They must already have tumor surgery planned at the NIH. A lab method called SmartMatch tests small pieces of the removed tumor against different drugs.
Where it stands. The team wants to see if SmartMatch can finish its report within 21 days of surgery. They also want to learn more about these tumors. The study has not reported results yet.
What this means, and what it doesn't
What it could mean: The report is shared with the patient and their local doctor. Together they can decide whether to use it in the treatment plan. No extra surgery is done for this study. Someone who fits might ask their care team about it.
What it doesn't mean: This study is a test, not a proven treatment. The study itself warns that the lab report may or may not be helpful. Taking part is not a promise of benefit. It is not a cure.
Source: ClinicalTrials.gov, September 15, 2026 · Read the original
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