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Testing a drug called Lixumistat in people newly diagnosed with glioblastoma

Original title: Window of Opportunity Study of Lixumistat in Patients With Newly Diagnosed Glioblastoma

How far along is this research?

This is a trial that is enrolling or has been updated. It is not a finding yet.

This is an early first test of the drug in people.

Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.

The trial team last updated this record on . Always check the trial page for the latest.

The short version

This study is testing what a drug called Lixumistat does in people just diagnosed with glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary.

Who this trial is for. This trial is for people who were just diagnosed with glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary. It is testing a drug called Lixumistat to see what effect it has.

Where it stands. This trial has not reported results. It is measuring the effect of Lixumistat in people with new glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary. The answer is not in yet.

What this means, and what it doesn't

What it could mean: Nothing is known yet about how well this drug works. Someone who fits could ask their care team about this study.

What it doesn't mean: This does not mean Lixumistat works. A trial is a test, not a proven treatment. Being in one is not a promise that it will help you. It is not a cure.

Source: ClinicalTrials.gov, October 20, 2026 · Read the original

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