Testing a cell therapy called MT027 in glioblastoma that has come back
Original title: The GLIOMAX Study: MT027 Allogeneic CAR-T for Recurrent Glioma
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This is a middle stage test in people, and it is still being studied.
Status: Not yet recruiting. It has not opened yet. Ask your care team to watch for it if it looks like a fit.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study tests a cell therapy for people whose glioblastoma: A glioma that is given grade 4, the highest grade. It grows fast. Treatment usually starts soon after it is found. It often means surgery, then radiation and chemotherapy. See the glossary has come back.
Who this trial is for. This trial is for people with a type of glioblastoma: A glioma that is given grade 4, the highest grade. It grows fast. Treatment usually starts soon after it is found. It often means surgery, then radiation and chemotherapy. See the glossary called IDH-wildtype that has come back or is growing again. They must have already had standard treatment. It tests a cell therapy called MT027, given into the fluid spaces of the brain.
Where it stands. This trial has not reported results. It is measuring how safe MT027 is, how well people handle it, whether it helps, and how the body deals with it. The answers are not in yet. People are also followed for a long time after their last dose.
What this means, and what it doesn't
What it could mean: This is one more idea being tested for glioblastoma: A glioma that is given grade 4, the highest grade. It grows fast. Treatment usually starts soon after it is found. It often means surgery, then radiation and chemotherapy. See the glossary that has come back. If your situation sounds like the one above, you can ask your care team about it. They can tell you if it is worth looking into for you.
What it doesn't mean: This does not mean MT027 works. A trial is a test, not a proven treatment. Joining one is not a guarantee that you will be helped. And it is not a promise of a cure.
Source: ClinicalTrials.gov, September 29, 2026 · Read the original
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