Testing 5-ALA with ultrasound for glioblastoma in both sides of the brain
Original title: TMZ + RT + 5-ALA + LIDU SDT System for Newly Diagnosed Butterfly Glioma
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This is an early safety test in people.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This trial is testing how safe a drug plus ultrasound is for a brain tumor on both sides.
Who this trial is for. This trial is for people just diagnosed with glioblastoma: A glioma that is given grade 4, the highest grade. It grows fast. Treatment usually starts soon after it is found. It often means surgery, then radiation and chemotherapy. See the glossary in both sides of the brain. This kind is sometimes called butterfly glioblastoma. They get a drug called 5-ALA: A medicine you are given before some brain operations. The tumor soaks it up. Under a special light the tumor then glows, so the surgeon can see where it stops and healthy brain starts. See the glossary with ultrasound, along with their usual chemo and radiation.
Where it stands. The trial is looking at how safe this is and how well people handle it. It is also testing giving it both before and after the usual chemo and radiation are done. The trial has not reported results.
What this means, and what it doesn't
What it could mean: Someone with glioblastoma: A glioma that is given grade 4, the highest grade. It grows fast. Treatment usually starts soon after it is found. It often means surgery, then radiation and chemotherapy. See the glossary in both sides of the brain could ask their care team about this trial. An early trial like this one checks safety first, before anyone knows if it helps.
What it doesn't mean: This does not mean the treatment works. A trial is a test, not proven care. Being in one is not a promise that it will help you. It is not a cure.
Source: ClinicalTrials.gov, October 7, 2026 · Read the original
This plain-language summary was written by AI and published automatically after passing our automatic safety checks. How we write.