Testing 3D-Printed Mouth Guards to Shield Healthy Mouth Tissue in Children Having Brain Cancer Radiation
Original title: Evaluation of The Radioprotective Effect of 3D-Printed Intraoral Stents in Children With Brain Cancer.
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This study does not list a phase, so it is still an early test in people.
Status: Not yet recruiting. It has not opened yet. Ask your care team to watch for it if it looks like a fit.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This trial is testing whether a custom 3D-printed guard worn in the mouth can protect healthy mouth tissue during radiation for brain cancer.
Who this trial is for. This trial is for children with brain cancer who are having radiotherapy. It is testing 3D-printed resin stents, which are custom guards worn in the mouth. The team plans to try four different thicknesses, then test the best one in patients.
Where it stands. The trial has not reported results. The team plans to measure how much of the treatment radiation each stent thickness blocks. They also plan to look at mouth sores, gum health, radiation-related tooth decay, and what patients say about how they feel. The answers are not in yet.
What this means, and what it doesn't
What it could mean: Radiation for a brain tumor can also reach the mouth. That can cause mouth sores, gum problems, and tooth decay. This trial is asking whether a better-made mouth guard can lower that harm. A family whose child fits the description could ask their care team about it.
What it doesn't mean: This does not mean the 3D-printed stent works. A trial is a test, not a proven treatment. Joining a trial is not a guarantee that anyone will be helped. This is not a promise of a cure, and it is not a treatment for the tumor itself.
Source: ClinicalTrials.gov, July 21, 2026 · Read the original
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