Studying blood and urine during radiation for glioblastoma
Original title: Collection of Blood and Urine Samples in Patients Receiving Radiation Therapy for Glioblastoma Multiforme
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
No phase is listed, and this study collects samples to learn from rather than testing a treatment.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study looks at what happens in the blood and urine of people getting radiation for a brain tumor called glioblastoma: The fastest-growing type of glioma (grade 4). Treatment usually starts soon after diagnosis: surgery first, then radiation and chemotherapy. See the glossary.
Who this trial is for. This study is for adults 18 and older with glioblastoma: The fastest-growing type of glioma (grade 4). Treatment usually starts soon after diagnosis: surgery first, then radiation and chemotherapy. See the glossary multiforme who are getting radiation therapy, or who will get it as part of their care. It collects blood and urine before, during, and after radiation to look at blood cells and at two proteins, VEGF and MMPs.
Where it stands. This study has not reported results. It is measuring changes in blood cells and in the two proteins, which may be involved when cancer comes back. Researchers hope the samples will help them build new tests to measure radiation exposure. They also hope to learn which patients or tumors respond better to radiation. The answers are not in yet.
What this means, and what it doesn't
What it could mean: This study does not offer a new treatment. People in it keep getting the radiation their doctors already planned. Urine is collected in a cup. About 2 tablespoons of blood are taken through a needle in a vein. More samples may be asked for during treatment and in the 3-year follow-up period. Someone who fits this picture could ask their care team about it.
What it doesn't mean: A trial is a test, not a proven treatment. Being in one is not a guarantee that it will help you. It is not a promise of a cure. This study collects samples to learn from. It is not meant to treat your tumor.
Source: ClinicalTrials.gov, August 11, 2026 · Read the original
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