Rare tumors found in people with MEN syndromes
Original title: Analysis of the clinical profile of multiple endocrine neoplasia syndromes and the association with other tumors.
How far along is this research?
- Lab cells
- Animals
- Review
- Tested in people
This was tested in people. That is the most reliable kind of research we share.
This was a look back at patient records, not a test of any treatment.
The short version
Doctors looked back at patient records and found extra tumor types in people with MEN syndromes.
What was studied. MEN stands for multiple endocrine neoplasia. It is a group of rare genetic conditions. Doctors reviewed records of 182 patients from a MEN registry. 106 had MEN1 and 76 had MEN2.
What they found. Most people with MEN1 had parathyroid tumors (89.6%). In MEN2, medullary thyroid cancer was the most common (60.5%). A brain tumor called glioblastoma: A glioma that is given grade 4, the highest grade. It grows fast. Treatment usually starts soon after it is found. It often means surgery, then radiation and chemotherapy. See the glossary showed up in 1.3% of the MEN2 patients.
What this means, and what it doesn't
What it could mean: If you have MEN1 or MEN2, other kinds of tumors can also show up. Your doctor may want to watch for them. Tell your care team about new symptoms so problems can be found early.
What it doesn't mean: This does not mean MEN syndromes cause these other tumors. It was a look back at old records at one place. No treatment was tested. There is no new therapy here, and it is not a cure. The authors say more study is needed. This does not change your care by itself. Talk with your own doctor.
Source: PubMed, October 1, 2026 · Read the original
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