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Radiosurgery Before Surgery for Brain Tumors That Spread From Another Cancer

Original title: Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

How far along is this research?

This is a trial that is enrolling or has been updated. It is not a finding yet.

This is an early test in people, meant to check safety and find the right dose.

Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.

The trial team last updated this record on . Always check the trial page for the latest.

The short version

This trial tests giving focused radiation first, then surgery, to keep brain tumors from coming back.

Who this trial is for. This trial is for people with cancer that has spread to the brain, where the tumor can be removed by surgery. It tests radiosurgery given before the operation. Radiosurgery aims x-rays right at the tumor. The goal of that aim is to spare healthy brain tissue nearby.

Where it stands. This trial has not reported results. It is looking at whether the tumors come back after this treatment. It is also checking the side effects of the two treatments together, and trying to find the best radiosurgery dose. Those answers are not in yet.

What this means, and what it doesn't

What it could mean: Right now this is a study, not care your own doctor can give you. Someone whose situation seems to fit could ask their care team about it. The care team can say whether it makes sense to look into.

What it doesn't mean: This does not mean the treatment works. A trial is a test. Researchers are still trying to learn if it helps and how safe it is. Joining a trial is not a guarantee of any benefit. This is not a promise of a cure. Whether anyone can take part is decided by the trial team.

Source: ClinicalTrials.gov, August 6, 2026 · Read the original

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