Radiation to the Brain and Spine That Tries to Protect a Memory Area
Original title: Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This is a middle stage trial, so we do not know yet if it helps.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study tests a way to aim radiation at the brain and spine while sparing a memory area.
Who this trial is for. This trial is for people with breast cancer or non-small cell lung cancer. It is for cancer that has spread to the fluid and thin layers around the brain and spinal cord. The trial tests radiation to the brain and spine, given with proton therapy or VMAT. The plan lowers the dose to the hippocampus, a memory part of the brain.
Where it stands. The trial has not reported results. It is measuring how well this radiation works. It is also looking at whether sparing the hippocampus leads to fewer brain and nerve side effects. Those answers are not in yet.
What this means, and what it doesn't
What it could mean: Radiation to the brain and spine can reach more places the cancer may have spread. It can also harm a memory area of the brain. This trial is asking if a different aiming plan lowers that harm. If this sounds like your situation, you can ask your care team about it.
What it doesn't mean: This does not mean this radiation plan is proven. A trial is a test, not a treatment you can count on. Joining a trial is not a promise that it will help you. It is not a cure, and no one can promise you a spot.
Source: ClinicalTrials.gov, August 14, 2026 · Read the original
This plain-language summary was written by AI and published automatically after passing our automatic safety checks. How we write.